TABLE 1.
All
|
AVR only
|
AVR with TAS
|
Isolated TAS
|
||||||
---|---|---|---|---|---|---|---|---|---|
% | SE | % | SE | % | SE | % | SE | P value | |
No. (n), weighted | 50,395 | 3670 | 37,696 | 2564 | 11,020 | 1122 | 1679 | 162 | |
Age, y (mean, SEM) | 54.1 | 0.3 | 54.7 | 0.3 | 53.1 | 0.4 | 47.1 | 0.9 | <.0001 |
Age group (y) | |||||||||
18-30 | 6.1 | 0.4 | 6.3 | 0.4 | 4.3 | 0.4 | 12.9 | 2.2 | <.0001 |
>30-40 | 10.6 | 0.4 | 10.1 | 0.4 | 11.6 | 0.7 | 16.2 | 2.1 | |
>40-50 | 18.9 | 0.5 | 17.5 | 0.6 | 22.5 | 1 | 26.7 | 2.2 | |
>50-65 | 39.3 | 0.5 | 39.1 | 0.6 | 40.9 | 1 | 32.6 | 2.3 | |
>65 | 25.1 | 0.7 | 27 | 0.7 | 20.7 | 1.1 | 11.6 | 1.9 | |
Gender (female) | 27 | 0.5 | 28.2 | 0.6 | 21.9 | 1 | 31.3 | 2.4 | <.0001 |
Aortic dissection | 2.4 | 0.2 | 0.7 | 0.1 | 6.8 | 0.6 | 11.8 | 1.8 | <.0001 |
SBE | 3.5 | 0.2 | 4.2 | 0.3 | 1.5 | 0.3 | 0.5 | 0.4 | <.0001 |
Coarctation | 1.2 | 0.1 | 0.6 | 0.1 | 0.9 | 0.2 | 14.6 | 2.2 | <.0001 |
CABG | 21.7 | 0.6 | 22.3 | 0.5 | 20.6 | 1.8 | 14.2 | 1.6 | .04 |
TAA | 26.3 | 1.1 | 7.1 | 0.5 | 84.8 | 1.1 | 72.6 | 2.6 | <.0001 |
Mechanical valve | 50.3 | 2.2 | 50.4 | 2 | 50.2 | 3.2 | .94 | ||
Comorbidities | |||||||||
0 | 39.8 | 1.4 | 38.8 | 1.3 | 42 | 2.3 | 47.7 | 2.7 | <.0001 |
1 | 31.1 | 0.6 | 30.8 | 0.7 | 32 | 1.1 | 31.4 | 2.6 | |
2 | 17.6 | 0.6 | 18 | 0.6 | 16.8 | 1.2 | 13.4 | 2.1 | |
≥3 | 11.6 | 0.7 | 12.4 | 0.8 | 9.2 | 1 | 7.5 | 1.5 | |
Turner syndrome | 0.3 | 0.1 | 0.2 | 0.1 | 0.4 | 0.1 | 2.1 | 0.8 | <.0001 |
Marfan syndrome | 0.3 | 0.1 | 0.1 | 0.04 | 0.7 | 0.2 | 1.5 | 0.7 | <.0001 |
Teaching hospital | 74.4 | 2.4 | 72.7 | 2.4 | 79.1 | 2.9 | 80.7 | 3.7 | .0002 |
Hospital region | |||||||||
Northeast | 19 | 2.8 | 18.5 | 2.5 | 21.4 | 4.2 | 15.7 | 3 | <.0001 |
Midwest | 31.1 | 3.6 | 29 | 3.2 | 37.2 | 5.3 | 38 | 4.6 | |
South | 28.7 | 3.4 | 30.8 | 3.4 | 21.9 | 3.7 | 26 | 4.5 | |
West | 21.1 | 2.3 | 21.7 | 2.2 | 19.5 | 3.2 | 20.2 | 4.2 | |
Private insurance | 64.1 | 0.8 | 61.7 | 0.9 | 71 | 1.2 | 73.7 | 2.6 | <.0001 |
Died | 1.6 | 0.1 | 1.5 | 0.2 | 1.8 | 0.3 | 2.9 | 0.9 | .07 |
There was an increase in the overall number of AVR and TAS performed in patients with BAV in the United States over time. This increase was most marked for patients undergoing AVR and concomitant TAS. AVR, Aortic valve repair or replacement; TAS, thoracic aortic surgery; SE, standard error; SEM, standard error of the mean; SBE, subacute bacterial endocarditis; CABG, coronary artery bypass grafting; TAA, thoracic aortic aneurysm.