TABLE IV.

Nongerminomatous Germ Cell Patients' Tumor Characteristics and Treatment Outcome

Patient number	Sex/age (yrs)	Pathology	Site	Metastases	HCG mIU/ml blood/CSF	AFP ng/ml blood/CSF	Surg	Chemo resp	Status
2	M/12.5	Terato-chorio carcinoma	Pineal		2,424/220	10.5/4.5	GTR	Not eval	PFS 67 mos
5	F/13.9	Germinoma	Pituitary		5,496/not done	NL/not done	PR	PR (96%)	PFS 71 mos
9	M/16.3	None	Pineal		NL/NL	286/314	Shunt only	PRa	PFS 61 mos
10	M/16.9	Yolk-sac teratoma	Pineal		13/NL	5,190/26	75% resect	Early death	DOD 2 mos
12	M/18.11	Mixed yolk-sac	Pineal		13/not done	274/not done	PR	PD	DOD 15 mos
15	F/11.2	Germinoma	Pineal	Frontal horn	9,990/9,800	1,141/153	Biopsy	PRb	PFS 64 mos
22	M/10.4	Adenoca-teratoma	Pineal		NL/NL	NL/NL	GTR	Not eval	PFS 61 mos
24	M/11.6	Germ	Pineal	CSF periventricular	74/59	NL/NL	Biopsy	CRb	PFS 58 mos
25	M/7.11	None	Pineal		165/1,550	14/8	None	SDb	PFS 43 mos
26	M/10.7	Germ-chorio	Pineal		NL/471	NL/NL	GTR	Not eval b	PFS 52 mos
27	F/6.5	Germ-chorio	Supra-sellar		NL/2,392	NL/NL	PR	SDb	Died of a sz 21 mos
28	M/16.2	None	Pineal		200/74	80/12	None	SD	PFS 51 mos
29	F/14	Mixed germ	Supra-sellar		719/	3,247/	PR	CR	PFS 50 mos
30	M/10.4	Mixed yolk-sac terat	Pineal		4/	156/NL	GTR	Not eval	PFS 50 mos

Yrs, years; HCG, beta subunit of human chorionic gonadotrophin; CSF, cerebrospinal fluid; AFP, α-fetoprotein; chemo, chemotherapy; Resp, response; M, male; GTR, gross total resection; Eval, evaluable; PFS, progression-free survival; F, female; NL, normal; PR, partial response; resect, resection; DOD, dead of disease; germ, germinoma; CR, complete response; SD, stable disease; sz, seizure; terat, teratoma.

^aSerum β-hcg + a-fp normal (CSF not done).

^bSerum and CSF β-hcg + α-fp normalized.