Table 2. Scoring Parameters of Pharmacophore Hypotheses for BCR-ABL, ABCG2, and P-gp Inhibitory Data.

hypothesis	survival score	inactive score	survival inactive score	site score	vector score	volume score	selectivity	number of derivatives matched the hypothesis	activity of the reference ligand
BCR-ABL AADDRRR.2187	3.883	2.196	1.687	0.99	1.0	0.89	2.816	5	2.08
P-gp AADDRRR.990	3.955	2.28	1.669	1.0	1.0	0.95	2.708	4	–0.225
ABCG2 ADHRRR.12	3.558	2.196	1.356	0.84	0.96	0.76	2.487	7	0.125