Table 2. MC1R Variant Allele Frequency.* .
| MC1R Variants | Cases N (%) | Controls N (%) | P-value** | Allele Dominance (R/r) |
| V60L | 192 (21.94) | 146 (19.08) | 0.17 | r |
| V92M | 138 (15.77) | 129 (16.86) | 0.60 | r |
| R163Q | 98 (11.20) | 94 (12.29) | 0.54 | r |
| R142H | 11 (1.26) | 10 (1.31) | 0.90 | r |
| I155T | 18 (2.06) | 6 (0.78) | 0.05 | r |
| D84E | 30 (3.43) | 18 (2.35) | 0.25 | R |
| R151C | 205(23.43) | 114 (14.90) | <0.01 | R |
| R160W | 173 (19.77) | 121 (15.82) | 0.04 | R |
| D294H | 46 (5.26) | 19 (2.48) | 0.01 | R |
| Indels | 22 (2.51) | 6 (0.78) | 0.01 | R |
| Rare | 26 (2.97) | 14 (1.83) | 0.18 | R |
*Allele frequency is determined from the total number of chromosomes genotyped.
** Chi2 or Fischer's exact test, as appropriate.