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. 2014 Jul 8;9(7):e101507. doi: 10.1371/journal.pone.0101507

Table 3. Melanoma Risk of Genotypes Combining Indels and Rare Variants with Conventional MC1R Variants.

Genotype Cases (n = 875) Controls (n = 765) Unadjusted OR (95% CI) P-value
Consensus/consensus 163 216 Ref
rare/consensus 10 11 1.21 (0.50–2.91) 0.68
Indel/consensus 11 4 3.65 (1.14–11.65) 0.03
rare/(R or r) 15 3 6.63 (1.89–23.27) <0.01
Indel/(r, R, or rare) 11 2 7.29 (1.59–33.34) 0.01

“R”: D84E, R151C, R160W, D294H.

“r”: V60L, V92M, R163Q, R142H, I155T.