Table 4.

Demographic and obstetrical characteristics of the population in the case-control study

	Normal Pregnancies (n=30)	Fetal Death (n=5)	p
Maternal age (years)	21.5 (19.8–23.2)	26 (21.5–36.0)	0.154
Gestational age at venipuncture (weeks)	32.9 (32.1–33.6)	33.4 (32–33.7)	0.493
Body mass index (Kg/m2)	26.1 (21.1–35.8)	24.6 (17.9–44.5)	0.873
Nulliparity	53.3%(16)	60% (3)	0.585
Tobacco Use	0	0	--
African American	80% (24)	80% (4)	0.90
Gestational age at delivery (weeks)	39.5 (38.9–40.6)	37.7 (34.7–38.9)	0.047
Birthweight (grams)	3273 (3165–3478)	2305 (1635–3360)	0.030
PlGF (pg/ml)	646 (279–1108)	97 (63–640)	0.016
sVEGFR-1 (pg/ml)	2779 (1822–4349)	6333 (3740–6908)	0.016
sEng (ng/ml)	7.5 (5.7–10.1)	23.8 (14.4–33.4)	0.002
PlGF/sVEGFR-1 ratio	0.25 (0.09–0.5)	0.02 (0.009–0.1)	0.002
PlGF/sEng ratio (pg/ng)	96 (28–167)	6.9 (2.3–28)	0.002

Value expressed as median (interquartile range) or percentage (number);

PlGF= placental growth factor, sEng= soluble endoglin, sVEGFR-1=soluble vascular endothelial growth factor receptor-1