Daily wheel-running activity for mutants and their wild-type littermates. Boxplots displaying the median, variability, and range of activity levels for light/dark (L/D) (A,B) and dark/dark (D/D) (C,D) light cycles. Genotypes are written across the x-axis, with wild-type littermates for each mutant genotype displayed individually. P-values for comparisons between individual mutant genotypes are indicated. Df (11)17–2/+ (n = 15), Rai1+/−(n = 9), Dexras1+/− (n = 22), Dexras1−/− (n = 24), Dp(11)17/+ (n = 22), wild-type littermates (n = 18 for Dexras1+/−, n = 29 for Dp(11)17/+, n = 13 for Df(11)17/+, and n = 14 for Rai1+/− littermates).