Table 2. Serum levels of metabolites (µmol/L) that were differentially expressed between controls and schizophrenia patients.
Compound | Levels in serum | ||
Controls (n = 27) | Schizophrenia patients (n = 25) | p value* | |
γ–Glutamylcysteine | 3.05±0.11 | 2.07±0.12 | 1.746E-06a |
Linoleic acid | 264±17.0 | 159±12.0 | 1.610E-05a |
D-Lactate | 7.26±0.481 | 13.1±1.42 | 2.426E-05a |
L-Tryptophan | 81.3±3.36 | 101±4.48 | 0.001011a |
Arachidonic acid | 55.4±4.48 | 38.5±2.18 | 0.001485 |
L-Kynurenine | 1.74±0.121 | 2.35±0.162 | 0.005676 |
D-Serine | 1.88±0.07 | 1.57±0.07 | 0.00163 |
Glutamate | 35.5±3.20 | 71.3±12.3 | 0.0145 |
3-Hydroxybutyrate | 46.5±10.1 | 17.6±3.84 | 0.004378 |
Glutathione | 3.67±0.241 | 3.03±0.149 | 0.03437 |
5-Hydroxytryptamine | 0.85±0.077 | 0.61±0.096 | 0.01308 |
Threonine | 126±7.44 | 111±10.3 | 0.0286 |
Tyrosine | 65.1±2.55 | 57.2±3.33 | 0.0469 |
Only p values below 0.05 are included in this table.
*Non-parametric Mann-Whitney U-test.
Significantly different following Bonferroni correction (<0.05/34).