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. 2014 Jul 8;9(7):e101652. doi: 10.1371/journal.pone.0101652

Table 2. Serum levels of metabolites (µmol/L) that were differentially expressed between controls and schizophrenia patients.

Compound Levels in serum
Controls (n = 27) Schizophrenia patients (n = 25) p value*
γ–Glutamylcysteine 3.05±0.11 2.07±0.12 1.746E-06a
Linoleic acid 264±17.0 159±12.0 1.610E-05a
D-Lactate 7.26±0.481 13.1±1.42 2.426E-05a
L-Tryptophan 81.3±3.36 101±4.48 0.001011a
Arachidonic acid 55.4±4.48 38.5±2.18 0.001485
L-Kynurenine 1.74±0.121 2.35±0.162 0.005676
D-Serine 1.88±0.07 1.57±0.07 0.00163
Glutamate 35.5±3.20 71.3±12.3 0.0145
3-Hydroxybutyrate 46.5±10.1 17.6±3.84 0.004378
Glutathione 3.67±0.241 3.03±0.149 0.03437
5-Hydroxytryptamine 0.85±0.077 0.61±0.096 0.01308
Threonine 126±7.44 111±10.3 0.0286
Tyrosine 65.1±2.55 57.2±3.33 0.0469

Only p values below 0.05 are included in this table.

*Non-parametric Mann-Whitney U-test.

a

Significantly different following Bonferroni correction (<0.05/34).