Table 2.
Summary of measurements in VDAART
| Enrollment (10–18 weeks gestation) |
Monthly | Third Trimester (32–38 weeks gestation) |
Delivery | Quarterly | 6 Months after delivery |
Year 1 | Year 2 |
Year 3 |
|
|---|---|---|---|---|---|---|---|---|---|
| Study Admission Criteria Questionnaire |
x | ||||||||
| Maternal Questionnaire | x | ||||||||
| Food Questionnaire (Maternal) |
x | x | x | x | |||||
| Food Questionnaire (Child) |
x | x | x | ||||||
| Baseline Sun Exposure Questionnaire |
x | ||||||||
| Follow-Up Sun Exposure Questionnaire |
x | x (mother and child) |
x (child) |
x (child) |
|||||
| Monthly Maternal Questionnaire |
x | x | |||||||
| Medical Record Review (electronic and/or paper) |
x | x | x | ||||||
| Determination of skin pigmentation |
x | x | x (mother and child) |
x (child) |
|||||
| Blood draw | x1 (mother) |
x1 (mother) |
x2 (cord blood) |
x1,3 (mother and child) |
x4 (child) |
||||
| Urine5 | x | x | |||||||
| Patient Health Questionnaire |
x | x | x | x | x | ||||
| Hardships Questionnaire |
x | x | x | x | |||||
| Labor and Delivery Form |
x | ||||||||
| Quarterly Infant Follow-up Questionnaire | x | x | x | x | |||||
| In-person visit | x | x | x | x | x | ||||
| Anthropometric Measurements |
x (child) |
x (child) |
x (child) |
||||||
| MEMS information download |
x | x | x (after delivery) |
1
Mother: 25(OH)D, blood for DNA extraction and plasma (1 purple top tube) and gene expression studies (2 PAXgene tubes).
2
Cord blood: 25(OH)D, total IgE (2 tiger top red tubes for serum), and blood for DNA extraction (2 purple top tubes for buffy coats and plasma) and gene expression studies (2 PAXgene tubes).
3
Child: total and specific IgE 25(OH)D (1 purple top tube for plasma and buffy coat); Mother: 25(OH)D (1 purple top for plasma and buffy coat)
4
Child: total and specific IgE, 25(OH)D, and blood for DNA extraction (1 purple tube for plasma and buffy coat) and gene expression studies (1 PAXgene tube)
5
Urinary calcium, creatinine.