Table 1.
Demographic variables and neuropsychological test scores for each group
| OA |
aMCI |
naMCI |
AD |
ANOVA |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | M | SD | M | SD | M | SD | M | SD | F | p |
| Age (years) | 69.04 | 9.23 | 69.88 | 8.73 | 71.0 | 11.29 | 73.77 | 12.11 | 1.62 | .187 |
| Age range | 51–88 | 53–92 | 51–93 | 46–91 | ||||||
| Sex (F:M) | 24:29 | 47:35 | 14:16 | 14:16 | ||||||
| Ethnicity (% Caucasian) | 92.5% | 82.9% | 76.7% | 73.3% | ||||||
| Education (years)a,b | 17.51 | 2.14 | 16.34 | 2.89 | 16.53 | 2.64 | 15.73 | 2.59 | 3.51 | .016 |
| GDSa,c | 4.00 | 3.88 | 7.09 | 4.95 | 7.42 | 5.12 | 5.41 | 4.29 | 5.48 | .001 |
| MMSEa,b,d,e | 28.60 | 1.60 | 26.84 | 2.47 | 28.00 | 2.32 | 21.93 | 4.54 | 42.66 | <.001 |
| WAIS-III Block Designa,b,c,d,e | 13.37 | 2.96 | 9.59 | 3.07 | 10.43 | 2.81 | 6.75 | 3.46 | 31.37 | <.001 |
| Rey-O Copya,b,c,d,e | 32.68 | 2.59 | 28.92 | 5.47 | 28.57 | 4.55 | 21.60 | 10.38 | 22.80 | <.001 |
| WAIS-III Digit Symbol Codinga,b,c,d,e | 63.28 | 12.54 | 50.26 | 14.67 | 52.62 | 12.48 | 31.21 | 14.48 | 33.36 | <.001 |
| WAIS-III DS Forwardb,d,e | 6.73 | 1.24 | 6.40 | 1.22 | 6.54 | 1.07 | 5.50 | 1.28 | 6.80 | <.001 |
| WAIS-III DS Backwarda,b,d,e | 5.37 | 1.32 | 4.42 | 1.21 | 5.00 | 1.39 | 3.23 | 1.36 | 18.35 | <.001 |
| WMS-III LM-Ia,b,c,d,e,f | 41.76 | 8.98 | 25.21 | 11.30 | 35.38 | 8.31 | 13.50 | 9.27 | 57.81 | <.001 |
| WMS-III LM-IIa,b,d,e,f | 26.10 | 6.76 | 12.26 | 8.67 | 21.96 | 6.93 | 3.50 | 4.89 | 70.75 | <.001 |
| WMS-III VR-Ia,b,c,d,e,f | 80.92 | 13.34 | 60.28 | 19.50 | 70.97 | 14.63 | 29.7 | 15.65 | 63.01 | <.001 |
| WMS-III VR-IIa,b,c,d,e,f | 56.94 | 21.54 | 22.81 | 18.96 | 42.63 | 19.67 | 1.83 | 4.96 | 68.89 | <.001 |
| Rey-O – Recalla,b,c,d,e,f | 17.53 | 5.43 | 8.13 | 5.40 | 12.93 | 4.39 | 2.66 | 3.94 | 65.23 | <.001 |
| TMT-Part A (in sec)a,b,c,d,e | 27.34 | 10.09 | 40.12 | 18.96 | 33.90 | 10.03 | 71.07 | 45.88 | 24.73 | <.001 |
| TMT-Part B (in sec)a,b,c,d,e | 71.08 | 34.35 | 136.35 | 74.01 | 106.37 | 43.57 | 227.28 | 87.58 | 36.37 | <.001 |
| Boston Naming Testa,b | 57.71 | 1.79 | 50.97 | 8.96 | 53.20 | 8.42 | 47.20 | 9.25 | 13.38 | <.001 |
| FAS Fluencya,b,d,e | 43.53 | 10.52 | 34.98 | 12.93 | 40.63 | 16.19 | 26.93 | 11.41 | 12.52 | <.001 |
| Animal Fluencya,b,c,d,e | 21.89 | 4.56 | 17.71 | 5.14 | 18.53 | 5.64 | 11.73 | 6.01 | 24.46 | <.001 |
| Stroop Color (in sec)a,b,d,e | 65.42 | 12.42 | 78.86 | 26.88 | 69.10 | 16.14 | 100.83 | 30.03 | 16.35 | <.001 |
| Stroop Word (in sec)b,d,e | 49.87 | 10.37 | 55.71 | 15.49 | 51.00 | 10.37 | 67.46 | 18.25 | 10.60 | <.001 |
| Stroop Interference (in sec)a,b,d,e | 125.62 | 31.47 | 162.04 | 57.63 | 141.73 | 45.17 | 217.95 | 54.25 | 19.05 | <.001 |
Note. GDS = Geriatric Depression Scale (raw score out of 30; N = 178; Brink et al., 1982); MMSE = Mini-Mental State Examination (raw score out of 30; N = 195; Folstein, Folstein, & McHugh, 1975); WAIS-III = Wechsler Adult Intelligence Scale – 3rd Edition; Block Design (age-corrected scaled scores; N = 190; Wechsler, 1997a); Rey-O (raw score out of 36; N = 194; Meyers & Meyers, 1995); Digit Symbol Coding (N = 181; Wechsler, 1997b); DS = Digit Span (longest digit length; N = 181; Wechsler, 1997b); WMS-III = Wechsler Memory Scale – 3rd Edition; LM = Logical Memory (raw score out of 75 and 50 for LM-I and LM-II, respectively; N = 182; Wechsler, 1997b); VR = Visual Reproduction (raw score out of 104; N = 195; Wechsler, 1997b); TMT = Trail Making Test (N = 194 for part A and N = 190 for part B; Strauss et al., 2006); Boston Naming Test (N = 180); FAS and Animal Fluency (N = 195); Stroop (N = 189 for color and word trials, and N = 152 for interference). Non-Caucasian participants included African-American (n = 17), Hispanic (n = 11), and Asian (n = 5) individuals. Multiple one-way ANOVAs were completed on the demographic and neuropsychological data, with post hoc comparisons completed using a Dunnett's T3 procedure (equal variances not assumed).
Significant difference between OA and aMCI groups (p < .05).
Significant difference between OA and AD groups (p < .05).
Significant difference between OA and naMCI groups (p < .05).
Significant difference between aMCI and AD groups (p < .05).
Significant difference between naMCI and AD groups (p < .05).
Significant difference between naMCI and aMCI groups (p < .05).