Table 1. Average body weight, blood glucose concentration, and cataract prevalence in SE- or EE-housing animals.
Average of body weight (g) | Average of blood glucose concentration (mg/dl) | |||||
Time After vehicle or STZ injection | Control | Diabetes+SE | Diabetes+EE | Control | Diabetes+SE | Diabetes+EE |
0 days | 352±6 | 355±9 | 358±9 | 113±8 | 115±11 | 119±10 |
3 weeks | 411±14 | 357±13a | 353±13a | 112±4 | 508±22b | 504±16b |
7 weeks | 481±17 | 369±12b | 374±9b | 118±4 | 585±10b | 592±7b |
10 weeks | 517±11 | 371±19b | 388±22b | 114±3 | 566±20b | 584±16b |
Body weight and blood glucose levels in vehicle- or STZ-injected animals at different time points. STZ induced a significant decrease in body weight and an increase in blood glucose levels, which did not differ between SE- and EE-housed animals at all time points examined. Cataract occurrence was similar in both diabetic groups. Data are mean ± SEM (n = 10 animals per group).
: p<0.05,
: p<0.01 vs. aged-matched control animals, by Tukey's test.