Table 1. The inhibition of HLC-080 and Sorafenib on the proliferation of various cancer cells.
Cell lines | Organs | IC50 (µM) | |
HLC-080 | Sorafenib | ||
U251 | Brain | 20.81±3.51 | 33.24±5.23 |
SH-SY5Y | Brain | 45.36±5.24 | 32.70±5.81 |
MGC803 | Stomach | 15.68±3.95 | 20.83±4.18 |
BGC823 | Stomach | 26.94±4.75 | 37.26±5.41 |
Ketr3 | Kidney | 7.96±2.07 | 16.01±4.18 |
HT-29 | Colon | 1.83±0.35 | 9.37±1.18 |
HCT-8 | Colon | 5.53±1.29 | 18.27±3.52 |
HCT-116 | Colon | 5.66±0.96 | 12.93±2.89 |
HepG2 | Liver | 4.10±1.29 | 17.03±3.42 |
SMMC-7721 | Liver | 7.48±1.88 | 16.40±3.63 |
Bel7402 | Liver | 15.73±3.61 | 12.59±3.49 |
A549 | Lung | 27.64±4.77 | 29.60±4.61 |
A2780 | Ovary | 14.12±3.21 | 22.04±3.63 |
HELF | Normal lung | 23.77±2.11 | 25.53±2.51 |