Table 1. Characteristics of the investigated studies of the association between E-selectin gene polymorphisms (A561C, C1839T) and EH.
| SNP | First author | Year | Region | Ethnicity | Age | Sample size | Genotype(case group) | Genotype(control group) | GenotypingMethods | HWE(P) | |||||
| Case | Control | MM | Mm | mm | MM | Mm | mm | ||||||||
| rs5361 (A561C) | Li MN [9] | 2009 | Yunnan (China) | Hani | 52.2±10.5/50.6±9.7 | 172 | 133 | 149 | 22 | 1 | 120 | 13 | 0 | PCR-RFCA | 0.553 |
| Zheng WW [10] | 2009 | Xinjiang (China) | Kazak | 47.4±11.4/44.1±11.1 | 150 | 150 | 117 | 33 | 0 | 132 | 18 | 0 | PCR-RFCA | 0.434 | |
| Chen HL [11] | 2005 | Beijing (China) | Han | 46.1±12.5/42.2±14.7 | 347 | 315 | 323 | 15 | 9 | 305 | 6 | 4 | PCR-RFCA | 0.000 | |
| Song Y [12] | 2007 | Guangdong (China) | Han | - | 105 | 94 | 94 | 10 | 1 | 91 | 3 | 0 | PCR-RFCA | 0.875 | |
| Liu ZC [13] | 2006 | Heibei (China) | Han | 61.3±8.7/59±5.1 | 95 | 101 | 75 | 18 | 2 | 92 | 8 | 1 | PCR-RFCA | 0.112 | |
| Li Y [14] | 2003 | Hubei (China) | Han | 68.5±6.3/67.2±5.5 | 176 | 182 | 158 | 18 | 0 | 167 | 15 | 0 | PCR-RFCA | 0.562 | |
| Srivastava [15] | 2012 | Delhi (Indian) | Asian Indian | 51.6±7.2/49.7±10.4 | 240 | 290 | 142 | 94 | 4 | 244 | 44 | 2 | PCR-RFCA | 0.991 | |
| Wang Z [16] | 2012 | Xinjiang (China) | Han | 49.1±10.7/48.1±9.9 | 366 | 349 | 329 | 24 | 13 | 339 | 10 | 0 | TaqMan PCR | 0.786 | |
| Wang Z [16] | 2012 | Xinjiang (China) | Uygur | 54.4±8.0/55.9±8.7 | 309 | 299 | 273 | 22 | 14 | 276 | 23 | 0 | TaqMan PCR | 0.489 | |
| Wang Z [16] | 2012 | Xinjiang (China) | Kazak | 50.0±13.3/50.6±14.5 | 264 | 275 | 237 | 26 | 1 | 255 | 20 | 0 | TaqMan PCR | 0.055 | |
| Wang ZG [17] | 2010 | Beijing (China) | Han | 53.8±8.0/51.5±8.9 | 490 | 495 | 447 | 38 | 5 | 474 | 21 | 0 | TaqMan PCR | 0.630 | |
| Zhang JL [18] | 2007 | Yunnan (China) | Yi | 47.1±10.4/45.7±7.5 | 99 | 134 | 91 | 8 | 0 | 131 | 3 | 0 | PCR-RFCA | 0.896 | |
| rs5355 (C1839T) | Li MN [19] | 2009 | Yunnan (China) | Hani | 52.2±10.5/50.6±9.7 | 172 | 133 | 136 | 36 | 0 | 98 | 35 | 0 | PCR-RFCA | 0.081 |
| Wang Z [16] | 2012 | Xinjiang (China) | Han | 49.1±10.7/48.1±9.9 | 368 | 349 | 340 | 28 | 0 | 320 | 28 | 1 | TaqMan PCR | 0.644 | |
| Wang Z [16] | 2012 | Xinjiang (China) | Uygur | 54.4±8.0/55.9±8.7 | 307 | 299 | 286 | 21 | 0 | 266 | 33 | 0 | TaqMan PCR | 0.313 | |
| Wang Z [16] | 2012 | Xinjiang (China) | Kazak | 50.0±13.3/50.6±14.5 | 264 | 272 | 241 | 22 | 1 | 239 | 33 | 0 | TaqMan PCR | 0.287 | |
| Wang ZG [17] | 2010 | Beijing (China) | Han | 53.8±8.0/51.5±8.9 | 490 | 495 | 450 | 37 | 3 | 445 | 48 | 2 | TaqMan PCR | 0.547 | |
| Zhang JL [18] | 2007 | Yunnan (China) | Yi | 47.1±10.4/45.7±7.5 | 99 | 134 | 88 | 11 | 0 | 125 | 9 | 0 | PCR-RFCA | 0.688 | |
Abbreviations: M, major allele; m, minor allele; SNP, single nucleotide polymorphism; PCR-RFLP, polymerase chain reaction–restriction fragment length polymorphism; HWE, Hardy-Weinberg equilibrium.