Table 1. CaMKII from Drosophila melanogaster exhibit high homology with the product of human gene CaMK2D.
| CAMKII(D melanogaster) | CAMKH2D(H sapiens) | Score | Identities (%) | Positives | Gaps |
| Isoform A | Isoforms 2, 1 | 825 | 81 | 432/478(90%) | 3/478(0%) |
| Isoform B | Isoforms 2, 1 | 817 | 78 | 432/497(86%) | 22/497(4%) |
| Isoform C | Isoforms 2, 1 | 825 | 81 | 432/478(90%) | 3/478(0%) |
| Isoform D | Isoforms 2, 1 | 810 | 75 | 432/518(83%) | 43/518(8%) |
| Isoform E | Isoforms 2, 1 | 817 | 78 | 432/497(86%) | 22/497(4% |
| Isoform G | Isoforms 2, 1 | 816 | 77 | 432/504(85%) | 29/504(5%) |
| Isoforma H | Isoforms 2, 1 | 825 | 81 | 432/478(90%) | 3/478(0%) |
| Isoform I | Isoforms 2, 1 | 810 | 75 | 432/518(83%) | 43/518(8%) |
| Isoform J | Isoforms 2, 1 | 809 | 74 | 432/519(83%) | 44/519(8%) |
| Isoform K | Isoforms 2, 1 | 820 | 81 | 429/477(89%) | 9/477(1%) |
| Isoform L | Isoforms 1, 2 | 801 | 74 | 429/517(82%) | 49/517(9%) |
| Isoform M | Isoform 2 | 807 | 77 | 429/499(85%) | 31/499(6%) |
All isoforms of Drosophila melanogaster CaMKII were aligned with the human genome and we found that CaMKII of the fruit fly has high homology with the product of gene CaMK2D, the most important human cardiac variant. The table shows that all splice variants from Drosophila melanogaster possess high scores with splice variants 1 and 2 of CaMK2D gene.