Table 3.
Model | Adult versus Pediatric | New Pediatric Final Model | New Pediatric Model, Severe TBI only | New Pediatric Model, Excluding NAT |
---|---|---|---|---|
Population characteristics | GCS 3–12 | GCS 3–12 | GCS 3–8 | GCS 3–12 No NAT |
Prediction dataset | Maas et al[14] | Prediction Cohort | Prediction Cohort | Prediction Cohort |
Prediction N | 2,249 | 442 | 360 | 385 |
Validation dataset | Entire PCH Cohort | Validation Cohort | Validation Cohort | Validation Cohort |
Validation N | 632 | 190 | 144 | 167 |
AUC (95% CI) | 0.85 (0.80 – 0.89) | 0.80 (0.68 – 0.91) | 0.81 (0.70 – 0.92) | 0.92 (0.86 – 0.97) |
Cox's calibration regression | ||||
Intercept (95% CI) | 1.08 (0.57 – 1.60) | −0.43 (−1.10 – 0.24) | −0.32 (−0.99 – 0.36) | −0.24 (−1.07 – 0.60) |
Slope (95% CI) | 1.81 (1.46 – 2.15) | 0.86 (0.52 – 1.20) | 0.87 (0.50 – 1.24) | 1.08 (0.63 – 1.52) |
LRX2 (1) | 165.6 | 31.2 | 28.3 | 43.0 |
p | < 0.001 | < 0.001 | < 0.001 | < 0.001 |
Brier's score | 0.098 | 0.082 | 0.098 | 0.052 |
Figure | 3 | 4 |
GCS = Glasgow Coma Scale; NAT = Non-accidental Trauma; PCH = Primary Children's Hospital; AUC = Area under the curve; CI = confidence interval; LR = likelihood ratio test