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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pediatr Crit Care Med. 2014 Jul;15(6):554–562. doi: 10.1097/PCC.0000000000000150

Table 4.

Measures of discrimination, calibration, and overall fit for mortality prediction models in children with moderate or severe TBI

Model components Rotterdam alone – Final model GCS alone Rotterdam and GCS Rotterdam, GCS, mechanism, ISS
Prediction dataset Prediction Cohort Prediction Cohort Prediction Cohort Prediction Cohort
Prediction N 442 442 442 442
Validation dataset Validation Cohort Validation Cohort Validation Cohort Validation Cohort
Validation N 190 190 190 190
AUC (95% CI) 0.80 (0.68 – 0.91) 0.70 (0.62 – 0.78) 0.83 (0.72 – 0.94) 0.91 (0.84 – 0.98)
Cox's calibration regression
 Intercept (95% CI) −0.43 (−1.10 – 0.24) −0.12 (−1.27 – 1.03) −0.31 (−0.98 – 0.36) 0.20 (−0.55 – 0.94)
 Slope (95% CI) 0.86 (0.52 – 1.20) 1.13 (0.36 – 1.91) 0.89 (0.56 – 1.23) 1.13 (0.72 – 1.53)
 LRX2 (1) 31.2 15.2 37.0 59.6
p < 0.001 < 0.001 < 0.001 < 0.001
Brier's score 0.082 0.101 0.078 0.060
Figure 2

TBI = traumatic brain injury; GCS = Glasgow Coma Scale; ISS = Injury Severity Score; AUC = Area under the curve; CI = confidence interval; LR = likelihood ratio test