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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Cytotherapy. 2014 May 16;16(8):1121–1131. doi: 10.1016/j.jcyt.2014.02.012

Figure 5. IL13 mutein-CAR T cells kill IL13Rα1- and IL13Rα2-positive cells.

Figure 5

(A,B) IL13 mutein-CAR T cells (IL13Y-CAR, IL13K-CAR) killed Raji-IL13Rα1and Raji-IL13Rα2 cells in contrast to Raji and Raji-GFP cells in a standard 4h cytotoxicity assay. Controls (NT T cells or mhFAP-CAR T cells) exhibited no cytolytic activity (results for 2 donors are shown).