Table 4.
Comparison of the distribution of MCP1 rs1024611 polymorphic variants in anti-HBc positive/anti-HBs negative patients hemodialysis (HD) and anti-HBc positive/anti-HBs positive HD patients.
| Genotype | Anti-HBc positive/anti-HBs negative patients (frequency) | Anti-HBc positive/anti-HBs positive patients (frequency) | Odds ratio (95%CI) | Two-tailed P | Ptrend | Pgenotyping | Power (%) |
|---|---|---|---|---|---|---|---|
| All HD cases | |||||||
| n=43 | n=127 | ||||||
| AA | 20 (0.47) | 67 (0.53) | Referent | – | 0.473 | 0.766 | |
| AG | 18 (0.42) | 48 (0.38) | 1.256 (0.560–2.798) | 0.673 | 7.7 | ||
| GG | 5 (0.11) | 12 (0.09) | 1.396 (0.342–4.911) | 0.772 | 8.0 | ||
| AG+GG | 23 (0.53) | 60 (0.47) | 1.284 (0.606–2.732) | 0.595 | 8.5 | ||
| MAF | 28 (0.33) | 72 (0.28) | 1.220 (0.690–2.125) | 0.542 | 10.4 | ||
| HD cases without DM | |||||||
| n=32 | n=90 | ||||||
| AA | 16 (0.50) | 50 (0.56) | Referent | – | 0.504 | 0.790 | |
| AG | 12 (0.38) | 32 (0.36) | 1.172 (0.442–3.039) | 0.888 | 5.9 | ||
| GG | 4 (0.13) | 8 (0.09) | 1.563 (0.302–6.791) | 0.734 | 8.7 | ||
| AG+GG | 16 (0.50) | 40 (0.44) | 1.250 (0.514–3.036) | 0.736 | 6.8 | ||
| MAF | 20 (0.31) | 48 (0.27) | 1.250 (0.631–2.421) | 0.534 | 9.8 | ||
| HD cases with DM | |||||||
| n=11 | n=37 | ||||||
| AA | 4 (0.36) | 17 (0.46) | Referent | – | 0.727 | 0.803 | |
| AG | 6 (0.55) | 16 (0.43) | 1.594 (0.306–9.097) | 0.784 | 6.1 | ||
| GG | 1 (0.09) | 4 (0.11) | 1.063 (0.017–15.84) | 1.000 | 1.9 | ||
| AG+GG | 7 (0.64) | 20 (0.54) | 1.488 (0.310–8.103) | 0.836 | 6.4 | ||
| MAF | 8 (0.36) | 24 (0.32) | 1.190 (0.378–3.544) | 0.919 | 5.1 | ||
anti-HBc – antibodies to core antigen of hepatitis B virus; anti-HBs – antibodies to surface antigen of hepatitis B virus; DM – diabetes mellitus; MAF – minor allele frequency.