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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Tissue Eng Regen Med. 2013 Apr 1;9(11):E13–E26. doi: 10.1002/term.1736

Figure 1. BIO Treatment Enhanced Active Nuclear β-catenin Concentrations.

Figure 1

C3H10T1/2 transfection with DNA reporter plasmids (A). Active β-catenin (TOPFlash) shows a BIO-mediated increase compared to controls (FOPFlash) (****P<0.0001 vs. FOPFlash) (mean +/− SD) (B). Increased active β-catenin persists for 3 days after BIO-treatment before returning to basal levels (**p<0.01, ****p<0.0001 vs. 0 μM) (mean +/− SD) (C).