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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Tissue Eng Regen Med. 2013 Apr 1;9(11):E13–E26. doi: 10.1002/term.1736

Figure 4. BIO Enhances 2D MSC Expression Sox2, NANOG, Oct4, and Cyclin D1.

Figure 4

Profiles of Wnt target genes Sox2, NANOG, Oct4, and Cyclin D1 following 24 hr BIO treatment (Day 1) (A), and 18 days post-BIO treatment (Day 19) (B) of 2D cultured MSCs. Profiles are normalized to the housekeeping gene β-actin and 0 μM controls, and are expressed as a ratio of initial gene expression (day 0) prior to BIO treatment (**p<0.01, ***p<0.001, ****p<0.0001 vs. 0 μM) (mean +/− SD).