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. 2014 Jul 1;11:31. doi: 10.1186/1743-7075-11-31

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Copyright © 2014 Ebaid; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Spleen sections stained with anti-CD20+ antibodies to realize B cells. It shows the marginal zone and lymphatic follicles in the control (a, b), DM (c, d) and DMWP (e, f) groups. The number of B cells was reduced in the marginal zone (MZ) and lymphatic follicles (F) of the diabetic rats and increased in both areas in WP treated diabetic rats (×400). Values shown are the mean count of the CD-20 cells in both MZ and F (g) ± SD. *shows the significance (p < 0.05) in comparison to the control group.