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. 2014 Jul 1;11:31. doi: 10.1186/1743-7075-11-31

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Copyright © 2014 Ebaid; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Quantitative analysis of mRNA expression of AKT1 genes (a). Semiquantative PCR-mRNA expression and the supernatant levels of IFN-γ (b, c) and IL-2 (d, e). It was found that WP restores the polyfunctional T cells (IFN-γ and IL-2 producing cells that exhibit a high proliferation capacity). The mRNA expressions (f) and the supernatant level (g) of TNF-α, and the mRNA expressions of Fas (h). Samples from five animals were analyzed. Samples from five animals were analyzed, while a representative result from each group is presented in this figure. Values shown are mean values ± SD. *shows the significance (p < 0.05) in comparison to the control group. #shows the significance (p < 0.05) in comparison to the diabetic group.