Table 4.
Changes from baseline of CD4 + T cells and viral load by a longitudinal analysis.
| Parameters | Estimate | 95% confidence limits | P-value |
|---|---|---|---|
|
CD4
+
T cells/μl |
|
|
|
| Change per month in Anti-Tat Ab+ |
-1.6 |
-6.2; 3.0 |
0.4768 |
| Change per month Anti-Tat Ab– |
-8.9 |
-13.8; -3.9 |
0.0011 |
| IgG anti-Env (log10 titers) anti-Tat Ab+ |
133.4 |
-130.0; 396.8 |
0.3070 |
| IgG anti-Env (log10 titers) anti-Tat Ab– |
150.0 |
-40.7; 340.6 |
0.1178 |
| IgG anti-Gag (log10 titers) anti-Tat Ab+ |
-15.6 |
-141.6; 110.5 |
0.8014 |
| IgG anti-Gag (log10 titers) anti-Tat Ab– |
-56.0 |
-177.8; 65.9 |
0.3533 |
|
Viral load (log
10
copies/μl) |
|
|
|
| Change per month in Anti-Tat Ab+ |
0.005 |
-0.007; 0.018 |
0.3898 |
| Change per month Anti-Tat Ab– |
0.011 |
0.001; 0.021 |
0.0401 |
| IgG anti-Env (log10 titers) anti-Tat Ab+ |
0.26 |
-0.64; 1.16 |
0.5560 |
| IgG anti-Env (log10 titers) anti-Tat Ab– |
0.08 |
-0.67; 0.83 |
0.8249 |
| IgG anti-Gag (log10 titers) anti-Tat Ab+ |
-0.19 |
-0.57; 0.18 |
0.3006 |
| IgG anti-Gag (log10 titers) anti-Tat Ab– | -0.15 | -0.55; 0.26 | 0.4632 |
Multivariate analysis for repeated measures of longitudinal samples from 41 individuals (random-effect regression model). Anti-Env and anti-Gag Abs were assessed at baseline and at 6, 18 and 36 months.