Table 1.
MTS cytotoxic effect of GTT and HC on human glioma cancer cells (1321N1, SW1783, LN18)
| Cell lines | Compound | IC50 value (μg/ml) | Viability (% cells) a |
|---|---|---|---|
| Grade II |
Gamma-tocotrienol (GTT) |
100 ± 10.22 |
4.2 ± 1.34 |
| 1321N1 |
Hydroxy-chavicol (HC) |
75 ± 7.51 |
5.2 ± 0.89 |
| Grade III |
Gamma-tocotrienol (GTT) |
79 ± 5.29 |
5.5 ± 2.48 |
| SW1783 |
Hydroxy-chavicol (HC) |
95 ± 5.83 |
10.5 ± 2.04 |
| Grade II |
Gamma-tocotrienol (GTT) |
42 ± 2.52 |
5.1 ± 1.82 |
| LN18 | Hydroxy-chavicol (HC) | 119 ± 7.77 | 9.6 ± 1.66 |
aPercentage of cell viability after 24 h incubation of maximum concentration treatment (200 μg/ml) of each compound.
Viable cells (%) were expressed as the mean ± SD of three independent experiments.