Table 1.
No. | Sex | Age (yr) | Primary disease | Manifestation of encephalopathy | Diagnosis | Treatment/Outcome |
1 | M | 29 | SAP with ARDS. | 4th d of onset, restlessness, haziness, delirium. Pathological sign negative. | PE | Diazepam, haloperidol. Recovery |
2 | F | 51 | SAP | At onset, haziness, delirium. | PE | Recovery |
3 | M | 41 | SAP with ALI. | 4th d of onset, restlessness, sleepiness, haziness. | PE | Recovery |
4 | M | 34 | SAP with pseudocyst bleeding | SAP for 3 mo, 3rd d after pseudocyst operation, hallucination, delirium, conjugate gaze palsies, coma, suspected Kernig sign. Diffused pancreatic necroses. | PE | Death |
5 | F | 42 | SAP with ALI and shock | 9th d of onset, delirium, unconsciousness. | PE | Death |
6 | M | 31 | SAP with ARF and ARDS. | 33rd d after onset, restlessness, hebetude, unconsciousness, delirium. | PE | Death |
7 | F | 37 | Recovery Phase of AP | Protracted vomiting. No supplement of VitB1. 36th d after onset, diplopia, tinnitus, apathy, dizziness, horizontal nystagmus. CSF negative, MRI negative. | WE | VitB1, B12 im. Recovery after 4 d |
8 | M | 48 | Recovery Phase of SAP, with ALI and pseudocyst | 45th d of onset, diplopia, sleepiness, haziness, horizontal nystagmus, spatial disorientation, decreased tendon reflex. | WE. Once suspected PE | Fasting for 51 d, no VitB1 in TPN for 44 d. Recovery after 4-day’s administration of VitB1 |
9 | M | 37 | Acute recurrent pancreatitis with pseudocyst | Long fasting, no supplement of VitB1. Nausea, vomiting, dizziness, hypomnesia, alalia, diplopia, amentia, coma. Conjugate gaze palsies, active tendon reflex, ankle clonus positive. CSF: total cells 134, WBC 2; glucose, protein increased lightly. MRI: suspected focus of brain stem. | WE. Once suspected PE and encephalitis | Dexamethasone ineffective. Administration of VitB1, 400 mg/d. Death |
10 | F | 40 | Recovery phase of AP | 42nd d after onset, vomiting, dizziness, alalia, trance, amentia, sleeplessness, hyperspasmia, coma. Myosis, decreased tendon reflex. Pathological signs negative. CSF: protein positive; total cells 180, WBC 0; glucose, protein increased lightly. | WE. Once suspected viral encephalitis | Dexamethasone, acyclovir ineffective. Respirator. Death |
ALI: acute lung injury; ARF: acute renal failure; ARDS: acute respiratory distress syndrome; CSF: cerebrospinal fluid; TPN: total parenteral nutrition.