Table 3.

Relation between gene expression pattern and clinicopathological parameters (mean ± SD)

Clinical parameters	Ang-2	Ang-1	Ang-2/1	Tie2	VEGF
Tumor size (cm)
< 5 (n = 10)	0.267 ± 0.113	0.148 ± 0.089	2.175 ± 1.025	1.686 ± 0.550	0.552 ± 0.205
≥ 5 (n = 28)	0.748 ± 0.422	0.212 ± 0.082	3.880 ± 2.067	1.570 ± 0.990	1.213 ± 0.537
Histlogical grade
G1 (n = 12)	0.509 ± 0.320	0.168 ± 0.064	3.106 ± 1.409	1.511 ± 0.574	0.916 ± 0.497
G2 (n = 16)	0.633 ± 0.395	0.194 ± 0.081	3.543 ± 1.925	1.470 ± 0.726	1.095 ± 0.604
G3 (n = 10)	0.737 ± 0.512	0.234 ± 0.101	3.645 ± 2.470	1.921 ± 0.138	1.097 ± 0.585
Portal vein invasion
positive (n = 11)	1.152 ± 0.376	0.232 ± 0.053	5.096 ± 1.691	1.880 ± 1.494	1.791 ± 0.423
negative (n = 27)	0.405 ± 0.163	0.180 ± 0.092	2.753 ± 1.631	1.488 ± 0.500	0.732 ± 0.254
Metastasis
positive (n = 6)	1.320 ± 0.366	0.235 ± 0.061	5.912 ± 1.847	2.262 ± 1.734	2.007 ± 0.214
negative (n = 32)	0.490 ± 0.271	0.187 ± 0.088	2.967 ± 1.600	1.148 ± 0.619	0.857 ± 0.415
Tumor capsule
positive (n = 13)	0.308 ± 0.135	0.178 ± 0.112	2.078 ± 0.887	1.733 ± 0.424	0.579 ± 0.198
negative (n = 25)	0.783 ± 0.429	0.203 ± 0.068	4.135 ± 1.998	1.529 ± 1.056	1.278 ± 0.558