Table 2.
Distribution of C3435T alleles and genotypes (cases and controls) in the existing literature
| C | T | CC | CT | TT | |
| Glas, 2003 | |||||
| UC = 1231 | 111 (45) | 135 (55) | 19 (15) | 73 (60) | 31 (25) |
| CD = 135 | 130 (48) | 140 (52) | 26 (19) | 78 (58) | 31 (23) |
| IBD = 258 | 241 (47) | 275 (53) | 45 (17) | 151 (59) | 62 (24) |
| HC = 265 | 272 (51) | 258 (49) | 70 (26) | 132 (50) | 63 (24) |
| Schwab, 2003 | C | T | CC | CT | TT |
| UCa = 149 | 129 (43) | 169 (57) | 26 (17) | 77 (52) | 46 (31) |
| HC = 149 | 154 (52) | 144 (48) | 39 (26) | 76 (51) | 34 (23) |
| CD = 126 | 134 (53) | 118 (47) | 33 (26) | 68 (54) | 25 (20) |
| HC = 126 | 128 (51) | 124 (49) | 35 (28) | 58 (46) | 33 (26) |
| IBD = 275 | 263 (48) | 287 (52) | 59 (21) | 145 (53) | 71 (26) |
| HC = 275 | 282 (51) | 268 (49) | 74 (27) | 134 (49) | 67 (24) |
| Ho, 2005 | C | T | CC | CT | TT |
| UCc = 335 | 280 (42) | 390 (58) | 61 (18) | 158 (47) | 116 (35) |
| CD = 268 | 252 (47) | 284 (53) | 56 (21) | 140 (52) | 72 (27) |
| IBD = 603 | 532 (44) | 674 (56) | 117 (19) | 298 (50) | 188 (31) |
| HC = 370 | 354 (48) | 386 (52) | 82 (22) | 190 (51) | 98 (27) |
| Palmieri, 2005 | C | T | CC | CT | TT |
| UC = 468 | 488 (52) | 448 (48) | 124 (27) | 240 (51) | 104 (22) |
| CD = 478 | 503 (53) | 453 (47) | 125 (26) | 253 (53) | 100 (21) |
| IBD = 946 | 991 (52) | 901 (48) | 249 (26) | 493 (52) | 204 (22) |
| HC = 450 | 470 (52) | 430 (48) | 115 (26) | 240 (53) | 95 (21) |
| Potocnik, 2004 | C | T | CC | CT | TT |
| UC = 144 | 134 (47) | 154 (53) | - | - | - |
| CD = 163 | 161 (49) | 165 (51) | - | - | - |
| IBD = 307 | 295 (48) | 319 (52) | |||
| HC = 355 | 376 (53) | 334 (47) | - | - | - |
| Urcelay, 2006 | |||||
| UC = 311 | 317 (51) | 305 (49) | 87 (28) | 143 (46) | 81 (26) |
| CDb = 3031 | 369 (61) | 237 (39) | 122 (40) | 125 (41) | 56 (19) |
| IBD = 614 | 686 (56) | 542 (44) | 209 (34) | 268 (44) | 137 (22) |
| HC = 324 | 344 (53) | 304 (47) | 97 (30) | 150 (46) | 77 (24) |
UC = Ulcerative colitis, CD = Crohn’s disease, HC = healthy controls. aP = 0.045 (T vs C); P = 0.049 (TT vs CC). cP = 0.02 (T vs C); P = 0.04 (TT vs CC). bP = 0.006 (T vs C); P = 0.01 (TT vs CC). 1 Subjects not in Hardy-Weinberg equilibrium.