Table 4.
Summary of ORs and 95% CIs for different outcomes obtained at the meta-analysis
|
Fixed effects |
Random effects |
Heterogeneity test | ||||
| P value | OR (95% CI) | P value | OR (95% CI) | |||
| C3435T | Outcome CD T vs C (6 studies) | 0.519 | 0.968 (0.878-1.068) | 0.722 | 0.974 (0.842-1.126) | 0.09 |
| TT vs CC (5 studies) | 0.297 | 0.892 (0.720-1.106) | 0.472 | 0.900 (0.675-1.200) | NS | |
| G2677T/A | G vs T (4 studies) | 0.635 | 1.027 (0.920-1.145) | 0.635 | 1.027 (0.920-1.145) | NS |
| GG vs GT TT (3 studies) Outcome UC | 0.338 | 1.092 (0.912-1.308) | 0.338 | 1.092 (0.912-1.308) | NS | |
| C3435T | T vs C (6 studies) | 0.002 | 1.170 (1.062-1.289) | 0.003 | 1.178 (1.058-1.311) | NS |
| TT vs CC (5 studies) | 0.008 | 1.332 (1.080-1.644) | 0.017 | 1.367 (1.057-1.768) | NS | |
| G2677T/A | G vs T (4 studies) | 0.843 | 0.989 (0.887-1.103) | 0.862 | 0.986 (0.836-1.162) | NS |
| GG vs GT TT (3 studies) Outcome IBD | 0.947 | 0.994 (0.830-1.190) | 0.947 | 0.994 (0.830-1.190) | NS | |
| C3435T | T vs C (6 studies) | 0.083 | 1.074 (0.991-1.165) | 0.135 | 1.083 (0.976-1.201) | NS |
| TT vs CC (5 studies) | 0.225 | 1.116 (0.935-1.332) | 0.274 | 1.135 (0.904-1.426) | NS | |
| G2677T/A | G vs T (5 studies) | 0.351 | 1.041 (0.957-1.132) | 0.448 | 1.047 (0.930-1.178) | NS |
| GG vs GT TT (4 studies) | 0.366 | 1.065 (0.929-1.221) | 0.366 | 1.065 (0.929-1.221) | NS | |