Table 2.
Tumor entity | CP | Etiology of | AK release before | AK release 4 wk | AK release 8 wk |
cirrhosis | RFA | after RFA | after RFA | ||
HCC 1 | A | alcohol | 4.8 | 398.46 | 535.87 |
HCC 2 | A | Hep C | 3.26 | 421.66 | 645.9 |
HCC 3 | B | Hep C | 4.88 | 578.63 | 845.99 |
HCC 4 | A | alcohol | 3.95 | 865.66 | 1025.21 |
HCC 5 | B | alcohol | 5 | 465.7 | 732.13 |
HCC 6 | A | alcohol | 4.66 | 751.33 | 924.66 |
Mean | 4.42 | 580.24b | 784.96b | ||
(SD) | 0.68 | 190.81 | 181.73 | ||
Tumor entity | Primary | AK release before | AK release 4 wk | AK release 8 wk | |
RFA | after RFA | after RFA | |||
CRC metastasis 1 | Sigma | 2.13 | 568.32 | 816.55 | |
CRC metastasis 2 | Colon | 3 | 947.47 | 1298.25 | |
CRC metastasis 3 | Colon | 2.79 | 627.55 | 945.33 | |
CRC metastasis 4 | Sigma | 2.56 | 699.45 | 845.54 | |
CRC metastasis 5 | Rectum | 2.98 | 598.65 | 932.17 | |
CRC metastasis 6 | Colon | 2.27 | 621.46 | 889.66 | |
Mean | 2.62 | 677.15b | 954.58b | ||
(SD) | 0.37 | 139.38 | 175.42 |
Cells were co-incubated with PBMC isolated from each patient taken before, 4 and 8 wk after RFA. CP: Child Pugh-Score of patients with liver cirrhosis; LC: liver cirrhosis; HCC: hepatocellular carcinoma; CRC metastasis: patients with colorectal cancer metastastatic to the liver; Primary: location of the primary tumor; m.d.: missing data;
P < 0.0001 vs bioluminescence before RFA.