Table 4.
Comparison of liver function tests before and after vaccination
|
Before vaccination |
After vaccination |
P | |||
| Range | Median | Range | Median | ||
| Patients | |||||
| Total Serum Bilirubin (mg/L) | 4-210 | 7 | 3-250 | 7.5 | 9.5 |
| ALT (IU/L) | 19-163 | 42 | 19-136 | 27.5 | 0.11 |
| AST (IU/L) | 28-299 | 38 | 30-288 | 43 | 0.07 |
| Controls | |||||
| Total Serum Bilirubin (mg/L) | 3-6 | 5 | 1-6 | 4 | 4.8 |
| ALT (IU/L) | 9-21 | 18 | 10-27 | 17 | 0.93 |
| AST (IU/L) | 21-39 | 27 | 21-57 | 31 | 0.01b |
b
P < 0.01 vs controls before and after vaccination (Wilcoxon Signed Ranks Test). ALT: alanine aminotransferase; AST: aspartate aminotransferase.