Table 5.
OAS | CSS | DFS | LRS | DRS | |
N stage | |||||
uni- / multivariate: P = | 0.009 / NS | 0.05 / NS | 0.06 / NS | 0.09 / NS | 0.15 / NS |
CEA | |||||
uni- / multivariate: P = | < 0.001 / 0.007 | < 0.001 / NS | < 0.001 / 0.001 | < 0.001 / NS | 0.55 / 0.055 |
multivariate risk ratio: | CEA increase: 1.37 | CEA increase: 3.21 | CEA decrease: 0.91 | ||
(CI 1.09 – 1.73) | (CI 1.61 – 6.82) | (CI 0.76 – 1.00) | |||
CA 19-9 | |||||
uni- / multivariate: P = | < 0.001 / NS | 0.033 / NS | 0.22 / NS | 0.79 / NS | 0.62 / NS |
Tumor location | |||||
uni- / multivariate: P = | 0.34 / NS | 0.43 / NS | 0.4 / NS | 0.83 / NS | 0.37 / NS |
Adherence to adjacent structures | |||||
uni- / multivariate: P = | < 0.001 / NS | 0.004 / NS | < 0.001 / NS | 0.13 / NS | 0.019 / NS |
BMI before RT | |||||
uni- / multivariate: P = | 0.47 / NS | 0.55 / NS | 0.83 / NS | 0.83 / NS | 0.15 / NS |
Smoking | |||||
uni- / multivariate: P = | 0.79 / NS | 0.49 / NS | 0.71 / NS | 0.22 / NS | 0.31 / NS |
Hkt before vs after RT | |||||
uni- / multivariate: P = | 0.047 / NS | 0.35 / NS | 0.31 / NS | 0.87 / NS | 0.99 / NS |
LDH before vs after RT | |||||
uni- / multivariate: P = | 0.32 / NS | 0.69 / NS | 0.77 / NS | 0.37 / NS | 0.21 / NS |
Risk ratio with confidence interval (CI) is given if multivariate analysis (step down analysis) revealed a significant result. Five- and 10- year survival rates are given as OAS, CSS, DFS, LRS and DRS