Table 3.
Expression of CK18 in antral mucosa of patients with gastritis (H pylori positive and negative) compared to the control group
| Cytokeratin 18 expression |
Antral mucosa epithelium |
||||||
| H pylori+G | H pylori-G | CG | P | ||||
| n | % | n | % | n | % | ||
| Surface epithelium | |||||||
| Diffuse immunoreactivity | 32 | 56.1 | 14 | 82.3 | 5 | 50.0 | NS |
| Focal immunoreactivity | 24 | 42.1 | 2 | 11.8 | 3 | 30.0 | NS |
| Without staining | 1 | 1.7 | 1 | 5.9 | 2 | 20.0 | 0.043 |
| n (%) | 57 | 100 | 17 | 100 | 10 | 100 | |
| Foveolar epithelium | |||||||
| Diffuse immunoreactivity | 31 | 54.4 | 8 | 47.1 | 1 | 10 | 0.035 |
| Moderate/Strong | 30 | 52.7 | 8 | 47.1 | 1 | 10 | 0.045 |
| Weak | 1 | 1.7 | 0 | 0 | 0 | 0 | NS |
| Focal immunoreactivity | 20 | 35.1 | 1 | 5.8 | 0 | 0 | 0.008 |
| Moderate/Strong | 5 | 8.8 | 0 | 0 | 0 | 0 | NS |
| Weak | 15 | 26.3 | 1 | 5.8 | 0 | 0 | 0.045 |
| Without staining | 6 | 10.5 | 8 | 47.1 | 9 | 90 | <0.001 |
| n (%) | 57 | 100 | 17 | 100 | 10 | 100 | |
| Glandular necks | |||||||
| Diffuse immunoreactivity | 36 | 63.2 | 13 | 76.5 | 6 | 60 | NS |
| Focal immunoreactivity | 18 | 31.6 | 2 | 11.8 | 2 | 20 | NS |
| Without staining | 3 | 5.2 | 1 | 5.9 | 2 | 20 | NS |
| n (%) | 57 | 100 | 17 | 100 | 10 | 100 | |
| Deep glands | |||||||
| Diffuse immunoreactivity | 15 | 26.3 | 8 | 47.0 | 4 | 40 | NS |
| Moderate/Strong | 15 | 26.3 | 5 | 29.4 | 3 | 30 | NS |
| Weak | 0 | 0 | 3 | 17.6 | 1 | 10 | 0.008 |
| Focal immunoreactivity | 18 | 31.6 | 3 | 17.7 | 4 | 40 | NS |
| Without staining | 24 | 42.1 | 6 | 10.3 | 2 | 20 | NS |
| n (%) | 57 | 100 | 17 | 100 | 10 | 100 | |
CG:control group; H pylori+G -:Helicobacter pylori positive patients with gastritis; H pylori-G: Helicobacter pylori negative patients with gastritis; NS: P > 0.05