Table 2.
Haematological analysis after administration of Chunggan extract for 4 wk
| Number of dogs |
Male (12) |
Female (12) |
||||||
| CGX (mg/kg•d) | 0 | 100 | 200 | 400 | 0 | 100 | 200 | 400 |
| Erythrocyte (M/UL) | 6.4 ± 0.6 | 6.80 ± 0.4 | 6.56 ± 0.4 | 6.70 ± 0.1 | 6.22 ± 0.5 | 6.70 ± 0.5 | 6.77 ± 0.5 | 6.59 ± 0.2 |
| Hemoglobin (g/dL) | 18.6 ± 2.1 | 17.6 ± 0.4 | 18.2 ± 1.0 | 18.1 ± 1.3 | 16.5 ± 1.7 | 17.5 ± 1.8 | 17.8 ± 0.4 | 17.7 ± 0.1 |
| Hematocrit (%) | 41.3 ± 4.1 | 42.8 ± 1.8 | 42.8 ± 2.2 | 42.2 ± 1.0 | 39.2 ± 2.8 | 40.1 ± 2.1 | 43.3 ± 3.9 | 41.6 ± 0.9 |
| MCV (fL) | 64.1 ± 0.3 | 63.1 ± 2.4 | 65.4 ± 2.8 | 62.9 ± 1.0 | 63.1 ± 0.1 | 60.1 ± 4.1 | 63.9 ± 1.4 | 63.1 ± 1.9 |
| MCH (pg) | 28.9 ± 1.1 | 26.0 ± 1.4 | 27.8 ± 2.3 | 27.0 ± 1.7 | 26.5 ± 1.2 | 26.1 ± 2.7 | 26.4 ± 2.4 | 26.8 ± 0.7 |
| MCHC (g/dL) | 45.2 ± 1.5 | 41.7 ± 0.6a | 42.4 ± 2.2 | 42.9 ± 2.2 | 42.1 ± 2.2 | 43.5 ± 2.5 | 41.3 ± 4.6 | 42.6 ± 0.7 |
| RDW (%) | 15.1 ± 0.1 | 15.9 ± 0.3 | 15.3 ± 0.4 | 15.9 ± 0.3 | 15.7 ± 0.1 | 15.9 ± 0.6 | 15.7 ± 0.5 | 15.1 ± 0.1 |
| Reticulocytes (%) | 0.30 ± 0.1 | 0.23 ± 0.1 | 0.37 ± 0.2 | 0.43 ± 0.2 | 0.77 ± 0.2 | 0.50 ± 0.4 | 0.53 ± 0.6 | 0.50 ± 0.2 |
| Platelets (k/UL) | 349 ± 13 | 320 ± 125 | 334 ± 50 | 344 ± 46 | 347 ± 94 | 333 ± 90 | 239 ± 87 | 245 ± 18 |
| MPV (fL) | 12.8 ± 0.3 | 15.1 ± 1.2 | 14.6 ± 2.2 | 14.0 ± 1.3 | 13.4 ± 1.6 | 12.8 ± 1.6 | 16.4 ± 4.2 | 15.0 ± 4.7 |
| PT (s) | 6.73 ± 0.2 | 7.20 ± 0.6 | 6.63 ± 0.3 | 6.77 ± 0.2 | 6.73 ± 0.3 | 7.00 ± 0.4 | 6.77 ± 0.1 | 6.93 ± 0.5 |
| aPTT (s) | 14.2 ± 0.5 | 19.3 ± 5.2 | 15.4 ± 0.7 | 15.2 ± 0.9 | 15.7 ± 0.2 | 15.4 ± 0.9 | 16.1 ± 2.6 | 16.5 ± 0.7 |
| Leukocytes (k/UL) | 9.86 ± 1.2 | 9.51 ± 1.3 | 8.56 ± 1.3 | 11.4 ± 1.4 | 9.64 ± 1.3 | 10.6 ± 0.2 | 11.8 ± 3.8 | 8.9 ± 1.6 |
| Neutrophil (%) | 61.0 ± 10 | 59.8 ± 15 | 65.7 ± 14 | 66.9 ± 10 | 57.0 ± 13 | 60.9 ± 14 | 49.2 ± 2.3 | 62.8 ± 13 |
| Lymphocyte (%) | 19.5 ± 4.1 | 23.7 ± 4.2 | 21.4 ± 4.7 | 21.8 ± 2.6 | 28.2 ± 5.2 | 26.7 ± 8.5 | 35.5 ± 13 | 27.1 ± 7.9 |
| Monocytes (%) | 7.5 ± 2.0 | 8.0 ± 3.2 | 6.9 ± 1.2 | 5.3 ± 0.9 | 7.2 ± 1.0 | 7.6 ± 5.7 | 10.4 ± 5.1 | 7.8 ± 2.2 |
| Eosinophil (%) | 11.6 ± 9.1 | 8.41 ± 4.2 | 5.96 ± 5.8 | 5.70 ± 1.7 | 7.47 ± 11 | 4.25 ± 1.9 | 4.15 ± 1.7 | 2.70 ± 2.4 |
| Basophil (%) | 0.30 ± 0.3 | 0.11 ± 0.1 | 0.12 ± 0.3 | 0.26 ± 0.2 | 0.31 ± 0.6 | 0.13 ± 0.1 | 0.34 ± 0.5 | 0.11 ± 0.1 |
After administration of Chunggan extract (CGX) for 4 wk, haematology was analysed to compare CGX-treated groups to the control group. MCV: Mean corpuscular volume; MCH: Mean corpuscular haemoglobin; MCHC: Mean corpuscular haemoglobin concentration; RDW: Red cell distribution width; MPV: Mean platelet volume; PT: Prothrombin time; APPT: Activated partial thromboplastin time. aindicates a significant difference at a level of P < 0.05.