Table 1.
Drug | 5-ASA (mesalamine or sulfasalazine) |
Dosage | 3.2-4 g/d |
Indications | Mild to moderately active disease, postoperative maintenance |
Important side effects | Headache, nausea and abdominal pain, often during treatment with sulfasalazine (in up to 45% of patients); thrombopenia; interstitial nephitis, pancreatitis; |
Monitoring | Liver function, full blood count and especially renal function |
Pregnancy | Suggested to be safe in conventional doses |