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. 2006 Aug 14;12(30):4813–4818. doi: 10.3748/wjg.v12.i30.4813

Table 1.

Prevalence data according to population and methodology of the study

Author (year of publication) Population characteristics Diagnostic assay Study type Prevalence
Criscuoli (2004) 42 pts with severe colitis HE-ICH on rectal biopsy + antigenemia pp65 prospective 21%
Kishore (2004) 63 pts with severe colitis (36 steroid resistant) Serology-HE and qualitative PCR prospective 16% 22%
Wada (2003) 47 pts with severe colitis Antigenemia prospective 34%
de Saussure (2004) 64 pts with active colitis Serology-viremia-antigenemia- HE-ICH prospective 1.5%-6%
Vega (1999) 267 active colitis HE-ICH retrospective 3%
Pofelski (2005) 48 pts severe colitis Quantitative PCR on colonic biopsies retrospective/ prospective 38% 60%
Kambham (2004) 40 pts steroid resistant (25 operated on for colectomy) HE-ICH retrospective Overall 25% Operated on pts 24%
Papadakis (2001) 1895 steroid resistant pts HE retrospective 0.5%
Cottone (2001) 19 Steroid resistant pts HE-ICH on rectal biopsy + antigenemia pp65 prospective 36%
Maconi (2005) 77 pts operated on for colectomy HE-ICH on surgical specimen prospective 22% overall 27% steroid resistant
Takahashi (2004) 69 surgical specimen of IBD pts HE-ICH on biopsy and surgical specimen retrospective 11.5%
Alcalà (2000) 39 pts operated on for colectomy HE + ICH retrospective 18%
Eire-Brook (1986) 26 pts operated on for colectomy Light and electron microscopy- ICH retrospective 11.5%
Cooper (1977) 46 pts operated on for colectomy HE retrospective 13%
Rahbar (2003) 23 pts with IBD (13 UC-10 CD) ICH+ in situ hybridization prospective 92/100%
Wakefield (1992) 50 pts with IBD (29 CD-21 UC) qualitative PCR prospective 66/81%