Table 4.
Comparison of diagnostic accuracy of FibroScan and other markers
| Fibrotic Area >10% | ||||||
| OC | Sens | Speci | SE | 95% CI | AUC | |
| FibroScan | 9.1 | 100 | 76.9 | 0.047 | 0.777 - 0.999 | 0.932 |
| HA | 96.0 | 76.5 | 84.6 | 0.080 | 0.618 - 0.924 | 0.803 |
| Col | 6.6 | 52.9 | 100 | 0.081 | 0.615 - 0.923 | 0.801 |
| APRI | 0.57 | 76.5 | 84.6 | 0.081 | 0.615 - 0.923 | 0.801 |
| Fibrotic Area > 20% | ||||||
| OC | Sens | Speci | SE | 95% CI | AUC | |
| FibroScan | 13.6 | 100 | 95.5 | 0.024 | 0.868 - 1.000 | 0.991 |
| HA | 106.0 | 100 | 77.3 | 0.061 | 0.797 - 0.993 | 0.946 |
| Col | 6.6 | 87.5 | 90.9 | 0.071 | 0.758 - 0.985 | 0.918 |
| APRI | 0.58 | 87.5 | 68.2 | 0.098 | 0.642 - 0.937 | 0.824 |
OC: Optimal cut off level; Sens: Sensitivity; Speci: Specificity; SE: Standard error; CI: Confidence interval; AUC: Area under the curve; HA: Hyaluronate; Col: Type IV collagen; APRI: AST-to platelet ratio index.