Table 3.
Histopathological changes of hepatic fatty degeneration after treatment with osthole 5-20 mg/kg for 6 wk in alcohol-induced fatty liver rats (n = 10)
Degree of fatty degeneration | Control | Model |
Osthole |
Lipanthyl 20 mg/kg | ||
5 mg/kg | 10 mg/kg | 20 mg/kg | ||||
— | 9 | 0 | 2 | 2 | 4 | 6 |
+ | 1 | 5 | 7 | 8 | 6 | 4 |
++ | 0 | 5 | 1 | 0 | 0 | 0 |
+++ | 0 | 0 | 0 | 0 | 0 | 0 |
P | < 0.01 | < 0.05 | < 0.05 | < 0.01 | < 0.01 |
P value for medicine-treated or control animal vs model animal.