Table 1.
Full and reduced logistic regression main effects models for the association between Crohn's disease, MAP infection, and the presence of a number of genetic polymorphisms of the NRAMP1 gene
|
Full model |
Reduced model2 |
||||
| Odds Ratio | P | Odds Ratio | P | ||
| MAP | Negative | 1.01 | 1.01 | ||
| Positive | 45.5 | < 0.001 | 42.4 | < 0.001 | |
| 1729 + 55del4 | +/+ | 1.01 | 1.01 | ||
| +/DEL, DEL/DEL | 5.6 | 0.014 | 5.6 | 0.011 | |
| 823 C/T | CC | 1.01 | 1.01 | ||
| CT | 75.6 | 0.001 | 50.8 | 0.001 | |
| D534R | GG | 1.01 | |||
| GC | 1.1 | 0.913 | |||
| (-)237C/T | CC | 1.01 | |||
| CT, TT | 0.5 | 0.350 | |||
| INT4 | GG | 1.01 | |||
| GC, CC | 2.5 | 0.224 | |||
| GT (n) | Allele1 | 1.01 | |||
| Allele2 | 1.2 | 0.807 | |||
| Allele3 | 0.6 | 0.673 | |||
1
Reference category;
2
Model statistics: Likelihood ratio test for equivalence with full model: P = 0.436; Pearson goodness-of-fit test: P = 0.407; Area under Receiver-Operating Characteristic curve: 0.886.