Table 2.
Effect of amphetamine on number and severity of indomethacin-induced gastric ulcerations (mean ± SE)
| Groups |
Number of
ulcerations/stomach |
Severity | ||
| TU | LU | UI | ||
| I (9) | I50 | 12.44 ± 3.69 | 10.11 ± 3.74 | 1.61 ± 0.31 |
| II (9) | I50 + A10 | 7.33 ± 1.89 | 5.44 ± 1.52 | 1.22 ± 0.25 |
| III (9) | I50 + A25 | 5.33 ± 2.38 | 3.11 ± 1.9 | 0.72 ± 0.21a |
| IV (8) | I50 + A50 | 2.25 ± 1.91c | 1.0 ± 1.0c | 0.31 ± 0.19b |
The subscript indices represent the doses expressed as μmol/kg. I: Indomethacin; A: Amphetamine. TU: Total number of ulcerations; LU: Large ulcerations (> 1 mm); UI: Ulcer index.
P < 0.05,
P < 0.01,
P < 0.05 vs groupI.