Table 2.

Comparison of pruritus scores in patients before and after placebo and naltrexone therapy (mean±SD)

Patients	1	2	3	1 and 2	1 and 3	2 and 3
(n = 34)	Before therapy	After placebo	After therapy	Significance	Significance	Significance
Pruritus in day	8.30 ± 1.07	7.54 ± 1.38	4.91 ± 2.56	P < 0.001	P < 0.001	P < 0.001
Pruritus in night	9.13 ± 0.78	8.29 ± 1.02	5.54 ± 2.51	P  < 0.001	P < 0.001	P < 0.001