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Effects of fluoride on DNA damage in rat oral mucosal cells and hepatocytes
| Groups | Cells |
Grade of DNA damage |
Rates of comet assay | ||||
| 0 | 1 | 2 | 3 | 4 | |||
| Control (oral mucosal cells) | 500 | 448 | 39 | 6 | 5 | 2 | 10.40 |
| Fluoride (oral mucosal cells) | 500 | 249 | 119 | 49 | 54 | 29 | 50.20b |
| Control (hepatocytes) | 500 | 453 | 23 | 12 | 9 | 3 | 9.40 |
| Fluoride (hepatocytes) | 500 | 276 | 127 | 52 | 31 | 14 | 44.80b |
P < 0.01 vs control group.
