Table 2.
IL-8 -251 A/T polymorphism, cagA status and vacA gene polymorphism in patients with gastric diseases
| Locus | Genotype | Patients Gastritis n (%) | Peptic Ulcer n (%) | Gastric Cancer n (%) | P value |
| IL-8 -251 | AA | 22 (14.4) | 14 (23.0) | 9.0 (47.4) | 0.013 |
| AT | 74 (48.4) | 28 (45.9) | 6.0 (31.6) | ||
| TT | 57 (37.3) | 19 (31.1) | 4.0 (21.1) | ||
| cagA | + | 148 (74.4) | 54 (80.6) | 17 (85.0) | 0.39 |
| - | 51 (25.6) | 13 (19.4) | 3.0 (15.0) | ||
| vacA | s1m1 | 48 (26.5) | 21 (32.3) | 12.0 (66.7) | 0.001 |
| s1m2 | 74 (40.9) | 33 (50.8) | 3.0 (16.7) | ||
| s2m2 | 59 (32.6) | 11 (16.9) | 3.0 (16.7) |