Table 2.
% of expression | % of hypomethylation | |||||
MAGE-A1 | MAGE-A3 | MAGE-A1 | MAGE-A3 | |||
Cancer cell lines | 59 | 66 | 81 | 81 | ||
Cancer tissues | NT1 | NT | 43 | 77 | ||
Normal tissues2 | NT | NT | 2 | 6 | ||
MAGE-A1 hypomethylation | MAGE-A3 hypomethylation | |||||
+ | - | P | + | - | P | |
Location | ||||||
Proximal | 14 (31.1%) | 31(68.9%) | 34 (75.6%) | 11 (24.4%) | ||
Distal | 17 (56.7%) | 13(43.3%) | 0.028 | 26 (86.7%) | 4 (13.3%) | 0.239 |
Sex | ||||||
Male | 17 (30.9%) | 38(69.1%) | 38 (69.1%) | 17 (30.9%) | ||
Female | 20 (62.5%) | 12(18.4%) | 0.004 | 29 (90.6%) | 3 (9.4%) | 0.021 |
Not tested;
Corresponding normal tissues of cancer tissues; +: Represent hypomethylation of MAGE genes; -: Represent no hypomethylation of MAGE genes.