Table 2.
cag A, vac A, IgG anti-H pylori and angiogenic factors in gastric cancer patients
|
IgG anti H pylori |
cag A |
vac A |
||||
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |
| With IgG- (≤ 7 U/mL) | With IgG+ (> 7 U/mL) | Negative for cagA | Positive for cagA | Cytotoxic strains (s1; m1/2) | Others (absent; s2m2) | |
| TP expression1 | ||||||
| 02 | 9 (31) | 20 (69) | 24 (57) | 18 (43) | 24 (60) | 16 (40) |
| > 0 | 2 (25) | 6 (75) | 8 (80) | 2 (10) | 8 (80) | 2 (20) |
| p53 expression1 | ||||||
| 02 | 8 (25) | 24 (75) | 27 (60) | 18 (40) | 28 (65) | 15 (35) |
| > 0 | 3 (60) | 2 (40) | 5 (63) | 3 (37) | 4 (50) | 4 (50) |
| MVD (CD34)1 | ||||||
| ≤ 372 | 7 (32) | 15 (68) | 16 (59) | 11 (41) | 15 (58) | 11 (42) |
| > 37 | 3 (21) | 11 (79) | 16 (64) | 9 (36) | 17 (71) | 7 (29) |
| VEGF-R1 expression1 | ||||||
| ≤ 202 | 6 (29) | 15 (71) | 16 (59) | 11 (41) | 14 (54) | 12 (46) |
| > 20 | 5 (31) | 11 (69) | 15 (58) | 11 (42) | 17 (68) | 8 (32) |
| pVEGF levels | ||||||
| ≤ 262 | 9 (50)a | 9 (50)a | 10 (53) | 9 (47) | 11 (61) | 7 (39) |
| > 26 | 2 (13)a | 13 (87)a | 9 (60) | 6 (40) | 9 (60) | 6 (40) |
| sVEGF levels | ||||||
| ≤ 4322 | 5 (29) | 12 (71) | 11 (61) | 7 (49) | 12 (71) | 5 (29) |
| > 432 | 6 (32) | 13 (68) | 9 (47) | 10 (53) | 9 (47) | 10 (53) |
sVEGF: Serum VEGF; pVEGF: Plasma VEGF;
1
% of immunostained cells;
2
Cut-off median value of the series;
a
P = 0.026.