Table 2.
MSTN+/+ | MSTN+/− | MSTN−/− | |
---|---|---|---|
EDL Muscles | |||
Pt (mN) | 110.78±4.84 | 136.76±12.33 | 160.87±8.07* |
sPt (mN/mm2) | 58.20±1.75 | 63.27±5.10 | 52.25±3.38 |
TTPT (ms) | 23.68±2.80 | 20.91±1.32 | 23.86±2.46 |
½RT (ms) | 22.56±1.48 | 20.80±1.02* | 15.51±0.25*# |
dP/dt (mN/ms) | 13.07±0.05 | 15.64±1.29 | 19.00±1.24*# |
Po (mN) | 461.19±14.69 | 520.53±18.48* | 616.93±17.10*# |
sPo (mN/mm2) | 243.32±10.04 | 242.12±8.22 | 199.86±7.37*# |
Soleus Muscles | |||
Pt (mN) | 47.12±2.78 | 60.43±5.00 | 65.52±5.85* |
sPt (mN/mm2) | 42.08±1.90 | 47.51±2.30 | 45.06±3.81 |
TTPT (ms) | 40.61±4.68 | 32.41±0.99 | 27.38±3.75 |
½RT (ms) | 50.10±5.42 | 47.55±2.13 | 37.57±1.92 |
dP/dt (mN/ms) | 4.20±0.21 | 4.91±0.33 | 6.08±0.80 |
Po (mN) | 295.84±7.49 | 324.94±18.52 | 385.06±17.57*# |
sPo (mN/mm2) | 265.81±10.10 | 257.15±6.34 | 264.84±8.50 |
Values are means ± SE. N = 6 muscles per genotype. Pt = peak twitch force; sPt = specific Pt; TTPT = time to peak twitch tension; ½RT = half-relaxation time; dP/dt = maximum rise in tension.
Significantly different from MSTN+/+ at P < 0.05.
Significantly different from MSTN+/− at P < 0.05.