Table 4. Statistical parameters of GH score validation for Hypo 1.

Parameter	Results
Total molecules in database (D)	800
Total number of actives in database (A)	43
Total Hits (Ht)	49
Active Hits (Ha)	39
% Yield of actives[(Ha/Ht)×100]	79.59
% Ratio of actives [(Ha/A)×100]	90.70
Enrichment factor (E) [(Ha×D)/(Ht×A)]	14.81
False negatives [A-Ha]	4.00
False positives [Ht-Ha]	10.00
Goodness of Hit Score (GH)a	0.81

^a [(Ha/4HtA) (3A+Ht)×(1−(Ht-Ha)/(D−A))]