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Autopsy specimen illustrating inflammation and remodeling responses in the asthmatic airway. (a) Airway inflammation and a central mucus plug (asterisk). ×10. (b) Increased muscle mass (asterisk) and submucosal gland hypertrophy (arrow). ×25. (c) Subepithelial fibrosis (asterisk) and eosinophilic infiltration (arrow). ×100.
