Table 4.

CG-1521 induces a budding index decrease in wild-type and gcn5Δ strains

Budding index analysis
Strain	Treatment	Budding index
		2 h	4 h
WT	Control	0.50 ± 0.05	0.48 ± 0.03
	50 μM CG-1521	0.30 ± 0.03*	0.16 ± 0.07*
	5 μg/mL α-factor	0.10 ± 0.05*	0.25 ± 0.03*
gcn5Δ	Control	0.44 ± 0.04	0.44 ± 0.07
	50 μM CG-1521	0.25 ± 0.04*	0.23 ± 0.07*
	5 μg/mL α-factor	0.12 ± 0.04*	0.33 ± 0.07

The budding index was determined as described in Methods. The data represent the mean ± SD of five independent biological replicates (*Comparisons are considered significant if p < 0.05 compared to control).