Table 1.
Demographic and Baseline Characteristics
| Patient Characteristics | Regimen A (TB) n=43 | Regimen B (ABC) n=51 |
|---|---|---|
|
| ||
| Median Age (range) | 57 (range: 25–82) | 57 (range: 22–83) |
|
| ||
| Male | 58.1% | 56.9% |
|
| ||
| Prior radiation therapy | 25.6% | 17.6% |
|
| ||
| Prior Systemic Therapies | ||
| None | 65.1% | 62.7% |
| Immunotherapy | 32.6% | 35.3% |
| Vaccine therapy | ---- | 2.0% |
| Immuno- and vaccine therapy | 2.3% | ---- |
|
| ||
| ECOG Performance Status | ||
| 0 | 74.4% | 64.7% |
| 1 | 25.6% | 35.3% |
|
| ||
| M1 sub stage | ||
| M1a | 23.3% | 23.5% |
| M1b | 30.2% | 25.5% |
| M1c | 46.5% | 51.0% |
|
| ||
| Elevated LDH (> ULN) | 47% | 51% |
|
| ||
| Pre-existing Signs and Symptoms | ||
| Grade 3 hypertension | ---- | 2.0% |
| Grade 2 hypertension | 4.7% | 3.9% |
| Grade 2 fatigue | 11.6% | 5.9% |
| Grade 2 muscle pain | 4.7% | 5.9% |
| Grade 2 joint pain | 0.0% | 7.8% |
| Grade 2 anemia | 2.3% | 2.0% |