Table 2.
More Common Toxicities Reported to be probably, possibly or definitely related to study treatment
| Regimen A (TB) (n=42) | Regimen B (ABC) Pre Add5 (n=28) | Regimen B (ABC) Post Add5 (n=23) | ||||
|---|---|---|---|---|---|---|
| Toxicity | any grade | ≥grade 3 | any grade | ≥grade 3 | any grade | ≥grade 3 |
| Anemia | 57% | 5% | 96% | 21% | 83% | 17% |
| Leukopenia | 36% | 10% | 75% | 29% | 74% | 26% |
| Neutropenia | 19% | 10% | 75% | 54% | 65% | 43% |
| Thrombocytopenia | 48% | 5% | 57% | 21% | 65% | 17% |
| Dyspnea | 2% | 2% | 18% | 14% | 9% | 0% |
| Fatigue | 88% | 10% | 93% | 21% | 87% | 9% |
| Hypertension | 52% | 2% | 29% | 7% | 17% | 0% |
| Nausea | 76% | 7% | 57% | 0% | 57% | 4% |
| Thrombosis | 5% | 5% | 18% | 14% | 9% | 9% |
| Vomiting | 43% | 12% | 11% | 4% | 30% | 0% |
| Neuropathy-sensory | 10% | 0% | 54% | 0% | 35% | 0% |